Hyperemesis Gravidarum (HG) is a condition in early pregnancy with intractable nausea, vomiting which leads to dehydration and electrolyte disturbances. We aimed to study the hospital utilization for HG across the United States using a nationwide representative sample.METHODS:
Data was collected from 2012 Healthcare Cost and Utilization Project National Inpatient Sample (HCUP-NIS). HCUP-NIS is the largest publicly available all payer inpatient database in the United States, consisting of sample of discharges from all hospitals participating in HCUP. Case was identified as all patients with pregnancy or delivery-related discharge code (ICD-9 code V27.0–V27.9) and with diagnosis of HG (ICD 9 codes 643.03, 643.13). SAS 9.4 software was used for statistical analysis.RESULTS:
On weighted analysis 3,779,078 pregnancies were identified and 24,485 admission occurrences were for HG. Admissions with primary diagnosis of HG: 79.7%; Age: <25 y: 42.1%, 25–34 y: 49.7%, ≥35 y: 8.2%; Race: Caucasian: 40.3%, African American: 34.1%, Hispanics: 17.7%, Others: 7.9%; Payer: Medicaid: 52.8%, Private Insurance: 35.8%, Self: 5.8%; Mean length of stay: 3.09 days (95% CI 2.99–3.19 days); Mean charge for admission: $14,920 (95% CI $14,224–$15,616); Mortality: 0%; Median Household Income: $1–38,999: 38.9%, $39,000–47,999: 25.3%, $48,000–62,999: 21%, $63,000+: 14.7%.CONCLUSION:
In our study, 0.65% of hospital admissions during pregnancies across the US were for HG. Overall cost of admissions in 2012 with the primary diagnosis of HG was around 300 million dollars. Early treatment of nausea and vomiting during pregnancy might prevent progression to HG and hospital admissions, which indeed might lower healthcare costs and improve quality of life during pregnancy.