Chorioamnionitis in Previable Delivery [20I]

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Abstract

INTRODUCTION:

The delivery of an extremely premature neonate prior to viability creates difficult decisions for health care providers and parents. The objective of this study is to describe the presence of chorioamnionitis in previable birth and its effect on length of life.

METHODS:

A retrospective cohort study of all live deliveries before 23 weeks gestation at a single urban tertiary care center from 2010 to 2014 was performed. Descriptive statistics were used to summarize patient characteristics.

RESULTS:

Forty-six cases of live birth at less than 23 weeks gestation from 40 pregnancies were identified. Mean length of life was 111 minutes and mean gestational age was 20 weeks 5 days. Histologic chorioamnionitis was identified on pathology in 32 of 37 (86.49%) placentas. Histologic chorioamnionitis had no significant impact on the length of survival of neonates after previable delivery (P=.371). Seven of 40 (17.5%) mothers were diagnosed with clinical chorioamnionitis in the antepartum or intrapartum period.

CONCLUSION:

Histologic chorioamnionitis was common among our cohort of previable deliveries. However, clinical chorioamnionitis was lower in our population.

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