Pregnant Women’s History of Vaccination and Acceptance of Hypothetical Zika Vaccine [15I]

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Promising Zika vaccines are currently in clinical trials. To prepare for public availability, the acceptability of a hypothetical Zika vaccine among pregnant women was assessed.


A short Likert-scale survey was administered to 100 pregnant women receiving routine prenatal care at the University of Kansas Medical Center from 07/07/2016 to 9/29/2016. Hypothetical vaccine acceptability was evaluated by calculating the proportion of respondents who strongly agreed with the statement “If a vaccine for Zika virus was available, I would get this vaccine while pregnant.”


Of 100 patients surveyed, 48% expressed strong agreement to getting a hypothetical Zika vaccine while pregnant. Women indicating strong vaccine acceptance were more likely than women not indicating strong vaccine acceptance to feel strongly about the importance of a recommendation from their prenatal provider (98% vs 63%, p<0.01), the importance of children being up to date on all their vaccinations (97% vs. 83%, p=0.01) and the importance of getting recommended vaccinations during her pregnancy (97% v. 79%, p=0.03). Data suggested that women who had received vaccines during pregnancy were more likely to be strongly interested in a hypothetical Zika vaccine (Tdap vs no Tdap: 51% vs 22%, p=0.08; influenza vaccine vs. no influenza vaccine: 55% vs 36%, p=0.07).


A Zika vaccine may be acceptable to pregnant women but would benefit from strong provider support and education about the risks and consequences of Zika infection and the benefits of vaccination.

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