Incidence and Characteristics of Cervical Cancer in Elderly Women [3Q]

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Abstract

INTRODUCTION:

Cervical cancer screening guidelines currently recommend cessation of screening after the age of 65 in the absence of previous dysplasia. Patients over the age of 65 are still susceptible to the disease however. This project aims to describe the incidence of cervical cancer in elderly patients as well as characteristics of their disease.

METHODS:

The American College of Surgeons’ National Cancer Database was queried for cervical cancer patients aged 18-99. Variables collected included age, grade, stage, and histology of the disease. Multivariate regression and Cox proportional hazard models were performed to analyze association between the variables as well as survival data.

RESULTS:

A total of 18,015 patients were included in the analysis. Of the patients included, 21% were over the age of 65. Older age was associated with higher grade and stage of disease at time of diagnosis (P<.0001). Older patients were also noted to do more poorly, with an increased risk of death of 1.3% for every year older a patient was at time of diagnosis (95% CI 1.0%-1.64%).

CONCLUSION:

Cervical cancer is as much a disease of the elderly as it is a disease of the young. It is important for clinicians to remain vigilant when screening for the disease and to obtain a proper history, including previous history of dysplasia, when treating these patients. Older patients diagnosed with the disease have typically more advanced and more aggressive disease than their younger counterparts.

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