0205 Spirometric changes in normal or early ilo pneumoconiosis radiographs of sandstone-dust exposed workers: a preliminary result

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ObjectivesTo estimate FEV1 decline after one-year follow-up among sandstone workers with normal or early abnormal ILO classification chest radiographs.Material and methodThe samples were sandstone workers with an ILO classification chest radiographs profusion CAG ≤1/1. FEV1 and FVC decline measured using follow-up FVC manoeuvre spirometry testing, plus work exposure, PPE and symptoms (if any) obtained through questionnaire interviews.ResultsThe 52 participants mostly were female, average age 48±8.9 years, and mostly non-smokers. Mean of deterioration of FEV1 at one-year follow-up was 105.4±131.7 mL (95% CI 68.7, 142.0) with increasing of FEV1 decline among high exposure, smokers and exposed ≥10 years. The mean FEV1 decline among workers with all those factors was 272.0±155.5 mL among workers with all those factors. Subgroup analysis with independent t-test and multiple linear regression models revealed only FEV1 decline after high exposure. FVC decline trended similarly. Mean of FVC loss was 119.4±181.1 mL (95% CI 68.9, 169.8) while mean FVC loss among those classified as high exposure smoking workers with ≥10 years exposure was 376.0±216.2 mL.ConclusionAlthough ILO chest radiographs were normal or near normal, the FEV1 and FVC declined among silica dust exposed workers,. Therefore FEV1 deterioration should be monitored in order to comply with the UK RCS Dust Exposed Surveillance Guideline, especially among high exposure

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