1713 Adverse neurologic health effects of occupational solvent exposure– from recognition to prevention

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Aim of the special sessionThe typical adverse neurological effect of long-term occupational solvent exposure is called chronic solvent encephalopathy, characterised by persistent neurocognitive symptoms, often leading to early retirement. Surprisingly, under detection of CSE occurs even in targeted health screens by occupational health services. The non-specific cognitive findings are challenging to interpret for clinicians and thus the improvement of protocols for the neuropsychological assessment are necessary. Not all exposed develop neurological dysfunction, does epigenetics reveal why neurobehavioural disorders develop. And finally, the question is addressed, does occupational solvent exposure increase the risk of neurodegenerative disease, such as Parkinson disease.Heidi Furu1, Prof. Christoph van Thriel2, Lode Godderis3, Brad Racette41Doctagon Oy and Finnish Institute of Occupational Health, Helsinki, Finland2Leibniz Research Centre for Working Environment and Human Factors, TU Dortmund, Dortmund, Germany3Environment and Health, Department of Public Health and Primary Care, KU Leuven and IDEWE, External Service for Prevention and Protection at Work, Belgium4Washington University School of Medicine, St. Louis, USA, and University of the Witwatersrand School of Public Health, Johannesburg, South Africa

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