840 Nafld and om practice

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Non-alcoholic fatty liver disease is an inflammation of the liver caused by an accumulation of fat deposits in the liver tissue. The common underlying problem is obesity, diabetes, or both in metabolic syndrome. NAFLD is manifested by an increase in alanine aminotransferase in liver function tests. Progressive disease results in cirrhosis if the cause remains untreated. Currently, NAFLD is an increasing problem in Asia as well as in the Philippines.


This is a review of literature on the emerging problem of NAFLD. Interventions focus on the individual and enterprise management of NAFLD.


Prevalence of NAFLD is 12.2% in a hospital-based Philippine study. The characteristic features included female, sex, obesity, elevated liver enzymes and diabetes. Another study compared ASH, NASH, and TASH and how disease progression is a result of both direct effects on the liver as well as indirect alterations in other organs and tissues such as intestine, adipose tissue, and immune system. In another study, the increasing incidence of NAFLD in Western countries is strictly linked to lifestyle habits. The prevalence of NAFLD in European and Japanese population-based studies is estimated to be 14% to 21%. One study presents lower prevalence that is variable between 15% to 20% in Asian countries than the Western countries.


Using the above results of the literature review, the paper discusses occupational management of individuals with NAFLD as well as the enterprise as a whole.


The occupational physician coordinates with the external physician for care of diagnosed workers with NAFLD, work accommodation, and fitness to return to work. Workplace management approaches discuss interventions to reduce if not prevent NAFLD due to workplace toxic and lifestyle agents.

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