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Occupational Psychosocial Risk Factors (OPRF) studies are a priority because may trig physical/mental health-effects. National studies confirm international investigations where exposure to unhealthy conditions can constitute a problem. National work regulations emphasise that jobs should achieve psychological well-being. This study identified OPRF in four ‘Manufacturing’ companies in Venezuela, measuring exposure magnitude associating them with self-perceived mental health.Observational-descriptive, field study. Psychosocial Risk Assessment was used and CoPSoQ-ISTAS 21, PAST 2.7 c for analysis. Questionnaire evaluates six Dimensions and 20 Factors. Results express exposure’s prevalence as the workers proportion in each situation: unfavourable (high risk), intermediate and favourable (low risk).Sample 576 workers. In all DIMENSIONS no high risk was greater than 37%. Social Capital/Compensations had the highest unfavourable situation (36.78% and 35.91%, respectively). Employment insecurity (favourable 57.93%), Working conditions (favourable 57.87%), Recognition (unfavourable 45.48%). Emotional demands reported greater risk (41.09%). Leadership Quality 50.09% and Predictability 53.34%. 60% of variables had significant correlation with anxiety/depression.Psychosocial risks were identified with low magnitudes dimensionally but there were 6 factors in high risk. Siegrist 1996 showed that unbalance Effort/Reward could damage health with stress repercussions. A high level of organisational justice has been linked to better mental health (Elovainio, et al., 2002). Results agree with Rodriguez-Martinez (2011) and Rodriguez-Bracho (2013), regarding exposure to emotional demands, predictability and leadership quality. Avendaño, et al (2009) found that relationships quality with superiors are important to face daily stressors. This also may indicate that company’ leaders lack of teams’ surveillance, with insufficient information to carry out the work expressed by Predictability. However, Colleagues/Superiors Social support, Clarity/Conflict roles and group feeling, were in favourable conditions. Factors as work compensation, social capital, emotional demands, leadership and predictability, were with greater consequences in mental health and employers must use important resources to manage daily stressors.