Predictive Value of the sFlt-1: PlGF Ratio in Women With Suspected Preeclampsia

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Abstract

Abstracted from N Engl J Med 2016;374:13–22

Preeclampsia, a heterogeneous, multisystem disorder defined by the new onset of hypertension and proteinuria after 20 weeks of gestation, affects 2% to 5% of pregnancies worldwide. The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is elevated in pregnant women before the clinical onset of preeclampsia, but its predictive value in women with suspected preeclampsia is unclear.

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