Risk of Fetal Loss Associated With Invasive Testing Following Combined First-Trimester Screening for Down Syndrome: A National Cohort of 147,987 Singleton Pregnancies

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Abstracted from Ultrasound Obstet Gynecol 2016;47:38–44

The risk of miscarriage after chorionic villus sampling (CVS) and amniocentesis (AC) was investigated in randomized clinical trials in the 1980s and 1990s. Studies have compared CVS with AC and found comparable risk of miscarriage after the 2 procedures.

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