Chorionic Villus Sampling, Early Amniocentesis, and Termination of Pregnancy Without Diagnostic Testing: Comparison of Fetal Risk Following Positive Non-invasive Prenatal Testing

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Abstract

(Abstracted from J Obstet Gynaecol Can 2016;38(5):441–445)

The accuracy of screening tests for fetal aneuploidy such as noninvasive prenatal testing based on cell-free DNA (cfDNA) techniques has improved remarkably over the past 40 years, thereby decreasing the likelihood of false-positive detection rates. Diagnostic tests such as early amniocentesis (EA) and chorionic villus sampling (CVS) have been recommended following positive first-trimester screening tests for confirmation.

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