Tenofovir to Prevent Hepatitis B Transmission in Mothers With High Viral Load

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(Abstracted from N Engl J Med 2016;374:2324–2334)

Hepatitis B virus (HBV), a leading cause of cirrhosis and liver cancer, is a serious health threat, and prevention of HBV transmission is an important part of the strategy to alleviate infection and its outcomes. Hepatitis B virus can be vertically transmitted from mothers to fetuses during childbirth, and infants who are untreated can consequently develop chronic infection.

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