Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study

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(Abstracted from J Clin Oncol 2017:35(13):1411–1420)For the randomized general population, the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) investigated a new multimodal screening test using the Risk of Ovarian Cancer Algorithm (ROCA), which interprets serial CA-125 results, and transvaginal sonography as a second-line test. High sensitivity and specificity were achieved with this test.

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