Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses

    loading  Checking for direct PDF access through Ovid

Abstract

Following activation, γδ T cells display many properties of lymphocytes from the innate immune system, yet how they mediate antigen presentation remains an open conundrum. In humans, circulating γδ T cells that express the Vγ9Vδ2 T-cell receptor become reversibly licensed for professional antigen presentation only upon interaction with a target cell opsonized with IgGs.

Related Topics

    loading  Loading Related Articles