A new strategy to target regulatory T cells in solid tumors

    loading  Checking for direct PDF access through Ovid

Abstract

The depletion of regulatory T cells (Tregs) is a promising therapeutic strategy to enhance antitumor immune responses. Our recent findings indicate that low doses of arsenic trioxide can delay tumor growth in murine models of colon and breast cancer by depleting Tregs through oxidative and nitrosative bursts.

Related Topics

    loading  Loading Related Articles