The potential impact of highly active antiretroviral therapy on the treatment and epidemiology of ranula in human immunodeficiency virus–positive patients

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Abstract

Objective.

The study's aim was to assess the potential therapeutic effect of highly active antiretroviral therapy (HAART) on ranulas in human immunodeficiency virus (HIV)–positive patients.

Study Design.

The study includes a retrospective observation of 3 patients who were initially part of a prospective study on the comparative effect of HAART on ranulas in 14 HIV-positive patients. These patients were clinically monitored while pursuing the medical treatment with HAART. Neither a fine needle aspiration nor a surgical procedure was performed. Clinical photographs were used for monitoring of any reduction in the ranula size. The effect of HAART on ranula was assessed at 3, 6 and 12 month.

Results.

A complete resolution of the ranula lesion was noticed in the 3 HIV-positive selected patients. These results were observed between 6 and 12 months period.

Conclusion.

This study suggests that HAART might present a potential therapeutic effect on ranula in HIV-positive patients.

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