In vitro evaluation of the sealing ability of MTA used for the repair of furcation perforations with and without the use of an internal matrix

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To evaluate the effect of matrix on mineral trioxide aggregate (MTA) when used to repair furcal perforations.

Study design.

Forty-five human molars with furcal perforations were randomly divided into 3 groups and repaired with MTA either alone or over a barrier (calcium sulfate or Collaplug). Eight teeth without perforations provided negative control samples. After assessing repair quality, 1 mol/L glucose solution was used as the tracer to detect the leakage. The concentration of leaked glucose was measured after 1, 2, 4, 7, 15, and 20 days using a glucose oxidase method.


No significant difference in either leakage or overfilling was found between the groups with Collaplug and MTA alone (P > .05). Although no overfilling was detected in the group with calcium sulfate, that group had the most leakage (P < .05).


Neither of the 2 internal matrices improved the sealing ability and reduced the incidence of overfilling simultaneously.

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