Thyrohyoid vocal fold augmentation with calcium hydroxyapatite

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To review the clinical results of the thyrohyoid approach for in-office vocal fold augmentation with calcium hydroxyapatite.


Retrospective chart review.


The charts of all persons who underwent in-office thyrohyoid vocal fold augmentation between June 1, 2005 and June 1, 2007 were reviewed. Information with respect to patient demographics, indications, complications, and clinical outcome was abstracted.


Fifty-one thyrohyoid vocal fold augmentations were performed in 33 patients (26 men; mean age, 66 years). Six (13%) procedures were aborted as a result of an inability to achieve an appropriate injection angle. Two (6%) self-limited complications included a vasovagal episode and a small ulcer near the petiole of the epiglottis. Pre- and postprocedure data were available for 62.5%. The mean 10-item Voice Handicap Index improved from 27.9 (±8.40) preprocedure to 13.5 (±10.52) postprocedure (P < 0.001).


In-office vocal fold augmentation with the use of the thyrohyoid approach demonstrates excellent clinical results. It has become our technique of choice for vocal fold medialization with the patient under local anesthesia in the office setting. Complications are rare.

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