Quality of Life in Acoustic Neuroma Patients

    loading  Checking for direct PDF access through Ovid



To examine the differences in quality of life for vestibular schwannoma patients undergoing conservative management, gamma knife, and surgery.


Vestibular schwannoma patients without a diagnosis of NF2.


Vestibular schwannoma treatment or conservative management.

Main Outcome Measures

Penn Acoustic Neuroma Quality of Life (PANQOL) survey scores (0–100).


One hundred eighty-six patients (98 conservative, 49 gamma knife, 39 surgery) were included. Mean patient age (years) of the surgery group (49 ± 14) was significantly younger than both the conservative (58 ± 13) and gamma knife group (59 ± 12) (p < 0.001). Mean follow-up time was 2.6 years.


Tumor size (mm) was found to be significantly different between the conservative (8 ± 4.8), gamma knife (18 ± 5.9), and surgery (22 ± 8.3) groups (p < 0.001). Speech recognition threshold and speech discrimination percentage were significantly better for the conservative group compared to the gamma knife or surgery groups (p < 0.001).


The hearing domain scores seemed better for the conservative group (62 ± 26) when compared to the surgery group (47 ± 25). The general and total domain scores were similar for all treatment groups, whereas the quality-of-life scores for gamma knife and surgery were similar.


Although surgery groups’ significantly larger tumors and worse hearing were apparent in specific PANQOL domains, all patients achieved a similar general level of quality of life.

Related Topics

    loading  Loading Related Articles