Cerebral Pilocytic Astrocytoma: Distinction from Infiltrating Fibrillary Astrocytomas

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Abstract

In spite of the common designation as a form of astrocytoma, pilocytic and fibrillary (diffuse) lesions are two distinct entities. One, the pilocytic, is generally discrete and hesitatingly invasive, slow-growing, and histologically stable over prolonged periods. The other, the fibrillary type, is infiltrating, rapidly growing in higher grade types, and prone to malignant degeneration. In light of the prognostic and therapeutic implications of the designations, every effort should be made to distinguish these lesions along the guidelines presented in this aricle.

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