SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 1-(5-ARYL-4-BENZOYL-3-HYDROXY-2-OXO-3-PYRROLIN-1-yl)-2-(3-BENZOYLMETHYLENE-2-OXOPIPERAZIN-1-yl)ETHANES

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Abstract

A series of l-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-3-pyrrolin-l-yl)-2-(3-benzoylmethylene-2-oxopiperazin-1-yl)ethanes have been obtained with 35-37% yields via reactions of benzoylpyruvic acid methyl ester with a mixture of aromatic aldehyde and diethylenetriamine in a 2: 1: 1 molar ratio.

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