INTRODUCTION OF PHARMACOPHORE GROUPS INTO BIS(INDOL-1-yl)MALEIMIDES AND 6H-PYRROLO[3,4: 2,3][1,4]DIAZEPINO[6,7,1-hi]-INDOLO-8,10(7H,9H)-DIONES

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Abstract

The synthesis of bis(indol-1-yl)maleimides and polycondensed [1, 4]diazepines containing various functional groups, which are the analogs of biologically active indolo[2, 3-à] carbazoles, is described. Functional groups were introduced directly into [1, 4]diazepine and bis(indol-1-yl)maleimide molecules via electrophilic substitution reactions using precursors containing such functional groups.

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