SYNTHESIS AND CORONARY VASODILATING ACTIVITY OF 1-AMINOPYRAZOLO[3,4-b]PYRIDINES WITH FUSED TETRAHYDROPYRAN (-THIOPYRAN) AND PIPERIDINE RINGS

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Abstract

Methods for the synthesis of 6,6-substituted 1-aminopyrazolo[3,4-b]pyridines with fused tetrahydropyran (-thiopyran) and pyridine rings have been developed on the basis of condensed 2-chloropyridine derivatives. The coronary vasodilating activity of the synthesized compounds has been studied.

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