SYNTHESIS, CHARACTERIZATION, AND THERMAL AND BIOCIDAL ASPECTS OF DRUG-BASED METAL COMPLEXES

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Abstract

Drug-based metal complexes [M(L)(A)(H2O)2] (M = Cu(II), Ni(II), Co(II), Zn(II), Cd(II), Mn(II), A = atenolol and L = ciprofloxacin) have been prepared and characterized using infrared spectra, electronic spectra, magnetic measurements, elemental analyses, and thermal investigation. Spectral investigations of metal complexes assume monomeric six-coordinate octahedral geometry. All the synthesized complexes exhibit higher biocidal activity against Bacillus subtilis, Escherichia coli, Bacillus cereus, Staphylococcus aureus, Salmonella typhi, and Serratia marcescens compared to parent compounds and standard drugs.

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