IR SPECTROSCOPIC STUDY OF INTERACTIONS IN THE ACETALDEHYDE-DOPAMINE-UNITHIOL TERNARY SYSTEM

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Abstract

IR spectroscopy has been used for the first comparative study of the kinetics of reaction of dopamine with acetaldehyde in the presence and absence of unithiol (sodium salt of 2,3-dimercapto-1-propanesulfonic acid, DMPS), a vicinal dithioglycol. Based on the analysis of these reactions, it is concluded that the rate of interaction between acetaldehyde and dopamine decreases significantly in the presence of unithiol, which is a new kind of pharmacological activity for unithiol. This property of unithiol allows it to be recommended for further investigation aimed at the development of a new remedy capable of inhibiting the development of alcohol addiction.

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