COMPARATIVE IN VITRO DISSOLUTION TESTING OF INDAPAMIDE PROLONGED-RELEASE TABLETS

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Abstract

The results of dissolution testing of five modified release dosage forms of indapamide are presented. It is shown that comparative analysis of dissolution profiles can be used to develop in vivo – in vitro correlations and to establish the similarity of drug bioavailability in various ready-to-use dosage forms for which the composition, technology, or scale of manufacturing may have been changed.

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