SYNTHESIS OF NEW PYRAZOLO[1,5-a]PYRIMIDINES

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Abstract

A series of condensed heterocycles containing the pyrazolo[1,5-a]pyrimidine moiety were synthesized from 5-amino-3-methyl-4-phenylpyrazole. The spectra of potential biological activity of the synthesized compounds were determined using computer-aided prediction methods, which showed that the most probable properties were corticotropin-releasing hormone antagonism, cyclooxygenase inhibition, and neuroleptic, nootropic, and cardioprotector activity

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