Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation


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Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxoïd stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors. Pediatr Blood Cancer 2008;51:545–548. © 2008 Wiley-Liss, Inc.

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