Pseudomonal Biofilm Topographic Distribution on Tympanostomy Tubes: An In Vitro Model

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In vitro growth of Pseudomonas aeruginosa biofilm on tympanostomy tubes showed that in Armstrong T-tubes, biofilm colonies were mainly located in the perpendicular junction between the body and the flanges, but in Paparella-type tube, they concentrated on the round rims. These “weakness” zones can be the future target areas for geometry changes, and can be specifically coated with antibiofilm materials.

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