Renal Metabolism in Fetal and Newborn Sheep
Cerebrovascular Hemodynamics during and after Recovery from Acute Asphyxia in the Newborn Dog
Effect of Environmental Hypothermia on Vitelline Artery Blood Pressure and Vascular Resistance in the Stage 18, 21, and 24 Chick Embryo
Perinatal Influences on in Vitro B Lymphocyte Differentiation in Human Neonates
The Effects of Chronic Fetal Hyperglycemia on Substrate Uptake by the Ovine Fetus and Conceptus
Long-Chain Acyl Coenzyme A Dehydrogenase Deficiency : An Inherited Cause of Nonketotic Hypoglycemia
Genetic Deficiency of Medium-Chain Acyl Coenzyme A Dehydrogenase : Studies in Cultured Skin Fibroblasts and Peripheral Mononuclear Leukocytes
Aldosterone Metabolism and Transepithelial Potential Difference in Normal and Cystic Fibrosis Subjects
Whole Body Protein Synthesis and Energy Expenditure in Very Low Birth Weight Infants
The Development of Antioxidant Enzymatic Defense in the Perinatal Rat Lung : Activities of Superoxide Dismutase, Glutathione Peroxidase, and Catalase
The Effects of Brain Blood Flow on Brain Bilirubin Deposition in Newborn Piglets
Prostaglandin Production and Zinc Depletion in Human Pregnancy
Transfer and Metabolism of Carnitine and Carnitine Esters in the in Vitro Perfused Human Placenta
Aminophylline Reduces Hypoxic Ventilatory Depression : Possible Role of Adenosine
The Chronically Reserpinized Rat as a Model for Cystic Fibrosis : Abnormal Cl− Transport as the Basis for Reduced Salivary Fluid Secretion
Defective Regulation of Immune Responses in Croup Due to Parainfluenza Virus
Morphologic and Metabolic Development of Human Fetal Epiphyseal Chondrocytes in Primary Culture
The Effect of Short-Term Starvation on Mucosal Barrier Function in the Newborn Rabbit
Pulmonary Toxicity of Monocrotaline Differs at Critical Periods of Lung Development
Regulation of Fetal Growth Presidential Address, Society for Pediatric Research, May 1984
THE EFFECT OF PHOSPHONOFORMIC ACID OH WILD TYPE AND MUTANT S49 CELL LINES : 1
CHARACTERIZATION OF HYDROXYUREA(HYU) RESISTANT S49 LYMPHOMA CELLS : 2
PURINE DE NOVO SYNTHESIS AND SALVAGE DURING TESTICULAR DEVELOPMENT IN THE RAT : 3
ALLOSTERIC CONTROL OF CTP SYNTHETASE IN VIVO : 4
ROLE OF THE NUCLEOSIDE TRANSPORT FUNCTION IN THE TRANSPORT, INCORPORATION, AND SALVAGE OF HYPOXANTHINE : 5
ALTERATION OF RIBONUCLEOTIDE AND DEOXYRIBONUCLEOTIDE METABOLISM BY INTERFERON IN HUMAN B-LYMPHOBLASTOID CELLS : 6
ETHANOL INDUCED NUCLEOTIDE CATABOLISM IN MOUSE T LYMPHOBLASTOID CELLS. : 7
EFFECTS OF ADA INHIBITION ON T CELL DEVELOPMENT IN Q VITRO. : 8
THE EFFECTS OF ADA INHIBITION ON B CELL DIFFERENTIATION IN THE RAT. : 9
ENHANCEMENT OF MTX CYTOTOXICITY BY URACIL ANALOGUES THAT INHIBIT CELLULAR dUTPase ACTIVITY : 10
PRPP SYNTHETASE SUPERACTIVITY IN LYMPHOBLAST LINES : 11
INHERITED PRPP SYNTHETASE SUPERACTIVITY' DUE : “TO ABERPANT INHIBITOR AND ACTIVATOR RESPONSIVENESS
13
FUNCTIONAL ANALYSIS OF A REMARKABLE EUKARYOTIC PROMOTER, THE HUMAN ADENOSINE DEAMINASE PROMOTER : 14
MECHANISM OF CYTOTOXICITY OF 2-CHLORO AND 2-BROMO DEOXYADENOSINE FOR A HUMAN LYMPHOBLASTIC CELL LINE, CCRF-CEM : 15
HORMONE-INDUCED ACCELERATION OF PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AND OF PURINE SYNTHESIS IN MOUSE LIVER IN VIVO : 16
PURIFICATION AND PROPERIES OF HUMAN DEOXYCYTIDINE KINASE : 17
SYNERGY OF METHOTREXATE AND 6-MERCAPTOPURINE ON CELL GROWTH AND CLONOGENICITY OF CULTURED HUMAN T-LYMPHO-BLASTS : 18
IDENTIFICATION OF A PURINE-SPECIFIC 5′-NUCLEOTIDASE IN HUMAN ERYTHROCYTES : 19
PATHWAYS OF ADENINE NUCLEOTIDE CATABOLISM IN HUMAN ERYTHROCYTES : 20
DECREASED PURINE AND METHIONINE SYNTHESIS IN PURINE NUCLEOSIDE TREATED T AND B LYHPHOBLASTS : REVERSAL BY HOMOCYSTEINE
COBALAMIN INACTIVATION DECREASES PURINE AND METHIONINE SYNTHESIS IN CULTURED HUMAN LYMPHOBLASTS : 22
HPLC PLASMA ADENOSINE ASSAY FOR USE IN CARDIAC STUDIES : 23
THE USE AND ABUSE OF ALLOPURINOL IN RENAL FAILURE THE TUMOUR LYSIS SYNDROME AND UROLITHIASIS : 24
HYPOXANTHINE TRANSPORT THROUGH HUMAN ERYTHROCYTE MEMBRANES : 25
PRIMARY GOUT IN AGING PATIENTS : 26
HYPOXANTHINE UPTAKE BY ISOLATED BRAIN MICRO-VESSELS : 27
5′ DEOXY-5′-METHYLTHIOADENOSINE (MTA) PHOSPHORYLASE DEFICIENCY IN LEUKEMIA : GENETICS AND BIOCHEMICAL ASPECTS
GENETIC ANALYSIS OF DEOXYADENOSINE TOXICITY IN DIVIDING HUMAN LYMPHOBLASTS : 29
MECHANISM OF ADENOSINE TOXICITY TO ADENOSINE KINASE DEFICIENT MAMMALIAN CELLS : 30
EXPRESSION OF HUMAN AND MOUSE HPRT MINIGENES : 31
THE MOLECULAR BASIS FOR THE HEREDITARY OVERPRODUCTION OF ADENOSINE DEAMINASE : 32
METABOLISM OF 5′-METHYLTHIOADENOSINE IN METHIONINE DEPENDENT AND INDEPENDENT CELLS : 33
APRT PARTIAL DEFICENCY IN A FAMILY : 34
ATP IN OXIDANT-INDUCED TISSUE INJURY : 35
PURINE NUCLEOTIDE AND DEOXYNUCLEOTIDE CATABOLISM IN HUMAN T LYMPHOCYTES : 36
ROLE OF INTRACELLULAR DEOXYNUCLEOSIDE TRIPHOSPHATES IN LEVELS IN DNA DAMAGE IN HUMAN PERIPHERAL BLOOD LYMPHOCYTES : 37
MORPHINE : SITES OF ACTION IN GUANOSINE NUCLEOSIDE PATHWAY
PARTIAL PURIFICATION OF SOLUBLE 5′-NUCLEOTIDASE FROM RABBIT HEART : 39
ELEVATED ERYTHROCYTE ADENOSINE DEAMINASE (ADA) ACTIVITY IN ACQUIRED IMMUNODEFICIENCY DISEASE (AIDS) : 40
RESTORATION OF IN VITRO FUNCTION OF ADENOSINE 41 DEAMINASE (ADA) DEFICIENT LYMPHOCYTES BY INTER-LEUKIN-2 (IL-2) : 41
EXPRESSION DEFECTS OF MUTANT HUMAN ADENOSINE DEAMINASE : 42
ON THE MECHANISM OF DEOXYRIBONUCLEOSIDE TOXICITY IN HUMAN T-LYMPHOBLASTOID CELLS; REVERSAL OF GROWTH IN HIBITION BY ADDITION OF CYTIDINE : 43
INCREASED LEVEL OF RIBONUCLEOTIDE REDUCTASE IN DEOXY ADENOSINE RESISTANT ADENOSINE DEAMINASE DEFICIENT HUMAN HISTIOCYTIC LYMPHOMA CELLS : 44
ISOLATION OF ADENOSINE DEAMINASE (ADA) cDNA SEQUENCES, CONTAINING THE ACTIVE SITE, BY COMPLEMENTATION IN ESCHERICHIA COLI : 45
STUDY TO DETERMINE RELATIVE HYPERURICAEMIC EFFECTS OF THE DIURETIC DRUGS BUMETANIDE AND FRUSEMIDE : 46
STUDY OF THE EFFECT OF HYPOURICAEMIC THERAPY ON SERUM LIPID LEVELS IN GOUT PATIENTS : 47
A MOLECULAR SURVEY OF HPRT DEFICIENCY : 48
GENE TRANSFER AMPLIFICATION, AND AN ANALYSIS OF MUTANTS IN THE UMP SYNTHASE GENE : 49
INFLUENCE OF METHOTREXATE ON PURINE AND PYRIMIDINI POOLS AND ON CELL PHASE DISTRIBUTION OF CULTURED HUMAN LYMPHOBLASTS : 50
DIHYDROTHYMINE DEHYDROGENASE DEFICIENCY IN A FAMILY LEADING TO ELEVATED LEVELS OF URACIL AND THYMINE : 51
INCREASED AVAILABILITY OF PHOSPHORIBOSYL PYROPHOSPHATE AS THE BASIS FOR ENHANCED 6-MERCAPTOPURINE INCORPORATION BY METHOTREXATE, IN CULTURED HUMAN LYMPHOBLASTS : 52
IMBALANCE IN NUCLEOTIDE POOLS OF MYELOID LEUKEMIA CELLS AND HL-60 CELLS : CORRELATION WITH CELL CYCLE PHASE,CELL PROLIFERATION AND DIFFERENTIATION
IMMUNOHISTOCHEMICAL DEMONSTRATION OF ADA AND ADCP ON THE CELL SURFACE OF HUMAN T-LYMPHOID CELLS : 54
ADENOSINE RECEPTORS ON HUMAN T LYMPHOCYTES AND HUMAN THYMOCYTES : 55
AMP-DEAMINASE AND CYTOSOLIC 5'NUCLEOTIDASE IN MURINE LYMPHOCYTE SUBPOPULATIONS : 56
PURINE AND MONOAMINE METABOLITES IN CEREBRAL SPINAL FLUID : 57
THE EFFECT OF ALLOPURINOL ON CEREBRAL SPINAL FLUID (CSF) PURINES IN HYPOXANTHINE-GUANINE PHOSPHORIBOSYL TRANSFERASE DEFICIENCY SYNDROMES : 58
SEPARATE MECHANISMS FOR CELLULAR UPTAKE OF PURINE NUCLEOTIDES BY B-AND T-LYMPHOBLASTS : 59
HGPRT deficiency with normal PRPP and APRT activity : 60
How can one define urate overproduction in man? : 61
USEFULNESS OF INTACT ERYTHROCYTE STUDIES IN THE DIAGNOSIS OF INHERITED PURINE AND PYRIMIDINE DEFECTS : 62
ZINC-MEDIATED URATE BINDING TO HUMAN ALBUMIN : 63
CORRECTED CLEARANCE IDENTIFIES UNDEREXCRETION OF URIC ACID IN A GOUTY KINDRED : 64
DUCHENNE MUSCULAR DYSTROPHY : NORMAL ATP TURNOVER IN CULTURED CELLS
BIOCHEMICAL AND GENETIC PROPERTIES OF HPRT CAPE TOWN : 66
GENETIC EXPRESSION OF ADENOSINE DEAMINASE (ADA) IN HUMAN LYMPHOID MALIGNANCIES : 67
EFFECTS OF DIPYRIDAMOLE AND 8-AMINOGUANOSINE ON INOSINE AND GUANOSINE LEVELS IN RAT BLOOD : 68
B-LYMPHOCYTES THYMOCYTES AND PLATELETS ACCUMULATE HIGH dATP LEVELS IN SIMULATED ADA DEFICIENCY : 69
ENHANCEMENT OF T CELL PROLIFERATION AND DIFFERENTIATION BY 8-MERCAPTOGUANOSINE : 70
ANTIGEN-SPECIFIC ENHANCEMENT OF THE HUMAN ANTIBODY RESPONSE BY A SUBSTITUTED NUCLEOSIDE : 71
INHIBITION OF DE NOVO PURINE SYNTHESIS BY METHYLTHIO ADENOSINE : 72
MECHANISM OF THYMINELESS DEATH : 73
DEOXY-ATP (dATP) LEVELS IN ADENOSINI 74 DEAMINASE (ADA) INHIBITED HUMAN PERIPHERAI BLOOD B AND T LYMPHOCYTES CULTURED IN DEOXYADENOSINE (AdR) : 74
INSERTION OF HYPOXAKTHINE PHOSPHORIBOSYLTRANSFERASE (HPRT) Cdna INTO HUMAN BONE MARROW CELLS (BMC) A RETROVIRUS VECTOR : 75
GENETIC AND BIOCHEMICAL CHARACTERISTICS OF THREE DIFFERENT TYPES OF MUTANTS OF CHINESE HAMSTER OVARY CELLS AFFECTED IN ADENOSINE KINASE : 76
PRODUCTION AND PROPERTIES OP MONOCLONAL ANTIBODIES AGAINST HUMAN ECTO-5′-NUCLEOTIDASE : 77
ECTOENZYMES OF NUCLEOTIDE METABOLISM ON HUMAN LYMPHOID CELLS : 78
EVIDENCE FOR A MEMBRANE ADENOSINE RECEPTOR IN LEISHMANIA MEXICANA MEXICANA (WR224) : 79
PURIFICATION OF MAMMALIAN GLYCINAMIDE RIBONUCLEOTIDE (GAR) SYNTHETASE : 80
SOURCE AND FATE OF CIRCULATING PYRIMIDINES : 81
PURINE NUCLEOTIDES IN HUMAN HEARTS DURING OPEN HEART SURGERY : 82
Inhibitor of 2' ,5′-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon : 83
DETERMINATION OF S-ADENOSYLHOMOCYSTEINE TISSUES FOLLOWING PHARMACOLOGICAL INHIBITION OF S-ADENOSYLHOMOCYSTEINE CATABOLISM : 84
COMPARISON OF E.COLI ADENINE PHOSPHOR IEO SYLTRANSFERASE AND OTHER PHOSPHORIBOSYL-TRANSFERASES : 85
HEMOLYTIC ANEMIA AND LOW RED CELL ATP/dATP RATIO IN GENETIC ADENOSINE DEAMINASE DEFICIENCY : 86
THE STABILIZATION OP ASCORBIC ACID BY URIC ACID : 87
INCREASED INOSINATE DEHYDROGENASE ACTIVITY IN MYOPHENOLIC ACID RESISTANT NEUROBLASTOMA CELLS : 88
REGULATION OF DEOXYADENOSINE AND NUCLEOSIDE ANALOG PHOSPHORYLATION BY HUMAN ADENOSINE KINASE : 89
EXPRESSION OF MURINE ADA cDNA IN E. COLI AND MAMMALIAN CELLS : 90
INCREASE OF AMIDOPHOSPHORIBOSYLTRANSFERASE ACTIVITY AND PHOSPHORIBOSYLPYROPHOSPHATE CONCENTRATION AS THE BASIS FOR INCREASED DE NOVO PURINE BIOSYNTHESIS IN THE REGENERATING RAT LIVER : 91
MECHANISM OF INCREASED RATE OF DE NOVO PURINE BIOSYNTHESIS IN RAT LIVER AFTER BILATERAL ADRENALECTOMY : 92
REGULATION OF THE CYTOSOL 5′-NUCLEOTIDASE OF THE HEART BY ADENYLATE ENERGY CHARGE : 93
HYPOURICEMIA DUE TO RENAL URATE WASTING : DIFFERENT TYPES OF TUBULAR TRANSPORT DEFECTS
HYPERURICEMIA AS POSSIBLE DIAGNOSTIC AID to FACTITIOUS-BARTTER'S SYNDROME : 95
CHARACTERISTICS OF HIGH AFFINITY AND LOW AFFINITY ADENOSINE BINDING SITES IN HUMAN CEREBRAL CORTEX : 96
DIAGNOSIS OF LESCH-NYHAN HETEROZYGOTES USING PERIPHERAL BLOOD : 97
JAPANESE PATIENTS WITH PARTIAL APRT DEFICIENCIES ACCOMPANIED WITH 2,8-DIHYDROXYADENINE LITHIASIS SYNTHESIZE MUTANT APRT WITH ALTERED KINETIC PROPERTIES WHICH DOES NOT FUNCTION IN VIABLE CELLS : 98
PURINE NUCLEOTIDE METABOLISM IN HUMAN NEUROBLASTOMA CELL LINES : 99
ISOLATION AND CHARACTERIZATION OF LEISHMANIA DONOVANI RESISTANT TO 5-FLUOROPYRIMIDINES : 100
ORGANIZATION OF THE HUMAN HYPOXANTHINE PHOSPHORIBO SYLTRANSFERASE GENE : 101
GLIAL CELLS METABOLICALLY COOPERATE : A POTENIAL REQUIREMENT FOR GENE REPLACEMENT THERAPY
5′-METHYLTHIOADENOSINE (MTA) PHOSPHORYLASE FROMLEISHMANIA DONOVANI : 103
HEMATOLOGIC TOXICITY PRODUCED BY PARENTERAL 6-THIOGUANINE IN MAN IS DOSE AND SCHEDULE DEPENDENT AND HIGHLY VARIABLE IN SEVERITY : 104
A LYMPHOHEMATOPOIETIC STEM CELL MODEL FOR ADENOSINEDEAMINASE (ADA) DEFICIENCY : 105
RENAL HANDLING OF URIC ACID UNDER METHYCLOTHIAZIDE ALONE OR ASSOCIATED WITH TRIAMTERNE : 106
6-THIOPURINE RIBOSIDE ANALOGS : THEIR TOXICITY ANDMETABOLISM IN LEISHMANIA DONOVANI AND MAMMALIAN CELLS
STUDIES OF PURINE BIOSYNTHESIS IN CHINESEHAMSTER CELL MDTANTS DEFICIENT IN ADENYLOSUCCINASE : 108
THE BIOSYNTHESIS OF DEOXYGUANOSINE TRIPHOSPHATE (dGTP) IN HERPES SIMPLEX TYPE-1 (HSV-1) INFECTED VERO CELL TREATED WITH ACYCLOVIR (ACV) AND HYDROXYUREA (HU) : 109
MULTIENZYME RNA SYNTHETASE COMPLEXES : METABOLIC CHANNELLING OF NUCLEOTIDE MONO- AND DIPHOSPHATE PRECURSORS INTO RNA
DOSE DEPENDENCY OF THE URIC ACID LOWERING EFFECTS OF ALLOPURINOL WITH AND WITHOUT ORAL PURINES : 111
UNPROPORTIONAL INCREASE IN HEMOLYSATE OF THE ACTIVITY OF A MUTANT HPRT DURING HEMODIALYSIS : 112
INHIBITION OF T CELL CYTOTOXICITY BY CYCLOSPORINE (CSA) ADENOSINE (ADO), AND AN INHIBITOR OF ADENOSINE DEAMINASE (ADA) : 113
A STUDY OF ADENOSINE DEAMINASES IN HUMAN SERA : 114
HUMAN PLACENTAL CYTOPLASMIC 5′-NUCLEOTIDASE : PURIFICATION AND MOLECULAR PROPERTIES
PURINE ENZYME ACTIVITIES AS MARKERS OF LYMPHOCYTIC DIFFERENTIATION : STUDIES OF LYMPHOCYTES FROM HORSES HORSES WITH SEVERE COMBINED IMMUNODEFICIENCY (SCID)
POST-MORTEM OXYPURINE CONCENTRATIONS IN THE CSF : 117
HYPOXANTHINE AND TETRAHYDROBIOPTERIN TREATMENT OF A PATIENT WITH FEATURES OF THE LESCH-NYHAN SYNDROME : 118
THE “SWITCH-OFF” MECHANISM OF SPONTANEOUS RESOLUTION OF ACUTE GOUT ATTACK : 119
RELATIONSHIPS BETWEEN LIPID AND PURINE METABOLISM : THE BEHAVIOR OF FATTY ACID IN THE PLASMA TRIGLYCERIDES OF GOUTY PATIENTS
THE EXCRETION OF OXALIC ACID IN GOUTY PATIENTS : 121
ADENOSINE RECEPTORS ON HUMAN BASOPHILS AND LUNG MAST CELLS : 122
ADENOSINE RECEPTORS ON HUMAN LYMPHOCYTES : 123
INHIBITION OF HAST CELL MEDIATOR RELEASE BY 5-AMINO-4-IMIDAZOLECARB0XAMIDE RIBOSIDE (AICAR) : 124
DETECTION OF mRNA FOR ADENOSINE DEAMINASE USING BIOTINYLATED PROBES : 125
LOW ADENINE NUCLEOTIDE POOLS IN BLOOM'S SYNDROME MAY REFLECT A DEFECTIVE SALVAGE PURINE BIOSYNTHESIS : 126
EFFECT OF FRUCTOSE INFUSION IN HEREDITARY XANTHINURIA EVIDENCE FOR GTP DEGRADATION : 127
DIMINISHED TUBULAR SECRETION OF URATE IN GOUT NOT DEPENDENT ON SERUM URATE LEVELS : 128
ROLE OF dATP THE INHIBITION OF NUCLEIC ACID SYNTHESIS IN ISOLATED NUCLEI : 129
URATE BINDING α2–GLOBULIN : SPECIFIC ANTIBODY PREPARATION
2'5'OLIGOADENYLATE SYNTHETASE IN HERPES VIRUS INFECATION AND AFTER INTERFERON TREATMENT : 131
IMMUNOPURINOGENIC ENZYMATIC ACTIVITY IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME : 132
PURINE SALVAGE ENZYMES IN TRICHOMONAS VAGINALIS : 133
EFFECTS OF 4-THIOADENOSINE ON HL-60 HUMAN PROMYELOCYTIC LEUKEMIA CELLS : 134
5-AZA-2′-deoxycytidine synergic action with thymidine : kinetic interaction of its monophosphate and triphosphate with dCMP deaminase
SEX STEROIDS INFLUENCE ON URIC ACID BINDING TO HUMAN PLASMA PROTEINS : 136
A SINGLE SYSTEM FOR THE EVALUATION OF PURINE AND PYRIMIDINE NUCLEOSIDES AND BASES TOGETHER WITH THEIR ANALOGUES IN BIOLOGICAL FLUIDS : 137
CHANGES OF PURINE METABOLISM DURING DIFFERENTIATION OF RAT HEART MYOBLASTS : 138
PURINE SYNTHETIC CAPACITIES OF DE NOVO AND SALVAGE PATHWAYS IN RAT HEPATOMA 3924A CELLS : 139
Modulation of Polymorphonuclear leukocyte function by adenosine analogues : 140
Suppression by metylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings : 141
Reversible interconversion between sulfo and desulfo xanthine dehydrogenase (oxidase) : 142
THE PREVALENCE OF PURINE METABOLIC DISORDERS IN JAPAN : 143
EFFECTS OF METHOTREXATE ON INTRACELLULAR NUCLEOTIDE METABOLISM AND ITS ROLE IN COMBINATION CHEMOTHERAPY : 144
CLASSIFICATION OF PURINE NUCLEOSIDE ANALOGS BASED ON MULTIPLE BIOLOGICAL AND BIOCHEMICAL PARAMETERS : 145
ON THE ROLE OF CYTIDINE DEAMINASE IN CELLULAR METABOLISM : 146
BONE MARROW TRANSPLANTATION IN LESCH-NYHAN DISEASE : 147
DEFICIENCY OF ERYTHROCYTE TYPE ISOZYME OF AMP - DEAMINASE IN HUMAN : 148
ANALYSIS OF MUTATION AT THE APRT LOCUS OF L-5178Y MOUSE LYMPHOMA CELLS : 149
l8FLOURODEOXYGLUCOSE PET SCANNING IN HPRT DEFICIENCY : 150
ADENOSINE RECEPTORS IN HPRT-DEFICIENT NEURO-BLASTOMA CELLS AND IN LYMPHOBLASTOID CELLS FROM LESCH-NYHAN PATIENTS : 151
DOPAMINE DEPLETION AND SELF MUTILATION IN THE RAT : A MODEL FOR LESCH-NYHAN DISEASE
ANALYSIS OF THE TRANSCRIPTIONAL REGULATORY SEQUENCES IN THE HAMSTER : 153
STUDIES ON THE ORGANIZATION AND STRUCTURE OF GENES AND ENZYMES OF PURINE SYNTHESIS IN ANIMALS AND MAN : 154
CYTIDINE DEAMINASE DEFICIENCY AND IMMUNODEFICIENCY MORE THAN A COINCIDENCE ? : 155
MODULATION OF CYTOTOXICITY AND METABOLISM OF 5-FLUOROURACIL (FU) IN TWO INTESTINE CELL LINES : 156
TOXICITY AND ANTITUMOR EFFECT OF 5-FLUOROURACIL (FU) 157 AND ITS RESCUE BY URIDINE (UR) : 157
URIDINE MONOPHOSPHATE KINASE : A NEW GENETIC MARKER OF SUSCEPTIBILITY TO HAEMOPHILUS INFLUENZAE TYPE B DISEASE
ADENOSINE TRANSPORT BY ISOLATED RAT LIVER MITOCHONDRIA : 159
THE SYNTHESIS OF PHOSPHORIBOSYLPYROPHOSPHATE FROM GLUCOSE DECREASES DURING AMINO ACID STARVATION OF HUMAN LYMPHOBLASTS : 160
METABOLISM OF PURINE NUCLEOTIDE IN THE LIVER AND IN THE KIDNEY OF CASTRATED RATS : 161
THE HORMONAL REGULATION OF PURINE BIOSYNTHESIS. CONTROL OF THE INOSINIC ACID BRANCH POINT : 162
CELLULAR PHARMACOKINETICS OF araCTP DURING THERAPY OF REFRACTORY ACUTE LEUKEMIA WITH araC : EFFECT OF m-AMSA
SPONTANEOUS VARIATIONS IN RENAL HANDLING OF URIC ACID : 164
SEX DIFFERENCES IN URIC ACID METABOLISM INADULTS : EVIDENCE FOR A LACK OF INFLUENCE OF ESTRADIOL-17β (E2)
URIC ACID METABOLISM IN PSORIASIS : 166
CELL CULTURE MODELS FOR THE STUDY OF PURINE METABOLISM IN HUMAN PLACENTAL TISSUE : 167
INVOLVEMENT OF SUBSTRATE CYCLES IN THE REGULATION OF PYRIMIDINE dNTP POOLS IN 3T6 MOUSE FIBROBLASTS : 168
URINARY OXIPURINOL-1-RIBOSIDE KXCEETION AND ALLOPURINOL-INDUCED OROTIC ACIDURIA : 169
ALLOPURINOL-1-RIBOSIDE FORMATION AND HGPRTDEFICIENCY : 170
IN VIVO INHIBITION OF MOUSE LIVER METHYLTRANSFERASE (MT) ENZYMES FOLLOWING TREATMENT WITH 2'DEOXYCOFORMYCIN (dCf) AND 2'DEOXYADENOSINE (AdR) : 171
RESIDUAL PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY IN A NEW DUTCH PATIENT WITH PNP-DEFICIENCY AND CELLULAR IMMUNODEFICIENCY : 172
Identification of uridylate nucleotidase as a potential target for 5-fluoro-5′-deoxyuridine in L1210 leukemia : 173
PURINE NUCLEOTIDE SYNTHESIS IN CULTURED RAT EMBRYOS UNDERGOING ORGANOGENESIS : 174
EFFECT OF DIETARY NUCLEOTIDES ON LYMPHOCYTE MATURATION : 175
Changes inlymphocyte adenosine deaminase(ADA) and purine nucleoside phosphorylase(PNP) levels in lung cancer after radical surgery : 176
KINETIC PROPERTIES OF HUMAN ERYTHROCYTE ADENOSYLHOMO CYSTEINASE : 177
REGULATORY ASPECTS OF HYPOXANTHINE UPTAKE BY HUMAN ERYTHROCYTES : 178
INFERENCES ON THE RAPID METABOLISM OF EXOGENOUSLY APPLIED.ATP IN ISOLATED SMOOTH MUSCLE PREPARATIONS USING PHARMACOLOGICAL STUDIES : 179
PHOSPHORYLATION OF 3-DEAZAGUANOSINE (3-DGR) BY CHINESE HAMSTER OVARY (CHO) CELLS : 180
THE EFFECT OF DEOXYGUANOSINE ON THE IN VITRO PROLIFERATION AND DIFFERENTIATION OF NORMAL HUMAN B LYMPHOCYTES : 181
THE INHIBITORY EFFECT OF DEOXYADENOSINE AND DEOXY GUANOSINE ON IN VITRO LYMPHOCYTE FUNCTION ARE EXPRESSED AT DIFFERENT STAGES OF LYMPHOCYTE ACTIVATION : 182
EVIDENCE AGAINST THE ADENOSINE-CATECHOL AMINE ANTAGONISM IN THE IN SITU DOG HEART : 183
ENZYME ACTIVITIES OF PURINE CATABOLISM AND SALVAGE IN HUMAN MUSCLE : 184
PURINE SALVAGE IN RAT HEART MYOBLASTS : 185
INTERMITTENT CONTROL OF HYPERURICEMIA IN THE TREATMENT OF GOUT : 186
BIOCHEMICAL BASIS FOR DEOXYADENOSINE AND 2-CHLORODEOXYADENOSINE TOXICITY TO BESTING HDMAN LYMPHOCYTES : 187
CHARACTERIZATION OF ARABINOSYLGUANINE (AraG) RESISTANCE IN A LYMPHOBLASTOID CELL LINE : 188
OROTIC ACIDURIA ASSOCIATED WITH THE FORM- IMINOTRANSFERASE/CYCLODEAMINASE DEFICIENCY : 189
Z-NUCLEOTIDE ACCUMULATION IN ERYTHROCYTES FROM LESCH-NYHAN PATIENTS : 190
TRANSITIONAL URATE CRYSTALS : A FACTOR IN GOUTY ARTHRITIS?
CORRELATIONS BETWEEN PURINE LEVELS, CLINICAL AND.IMMUNOLOGICAL STATUS IN ADA DEFICIENCY : 192
ERYTHROCYTE GTP DEPLETION IN PNP DEFICIENCY PRESENTING WITH HAEMOLYTIC ANAEMIA AND HYPODRICAEMIA : 193
A CASE OF LESCH NYHAN SYNDROME WITH DELAYED ONSET OF SELF MUTILATION : 194
INVESTIGATION OF PURINE UTILISATION IN CULTURED FIBROBLASTS, AMNIOCYTES AND CHORIONIC VILLI : 195
MYOADENYLATE DEAMINASE DEFICIENCY AND McARDLE'S DISEASE : PLASMA ADENOSINE, INOSINE AND HYPOXANTHINE AFTER ISCHEMIC FOREARM EXERCISE
SYNTHESIS AND TURNOVER OF PURINE NUCLEOSIDE PHOSPHORYLASE IN HUMAN LYMPHOCYTES : 197
ELEVATED ADENOSINE LEVELS IN NEWBORNS : 198
CARDIOVASCULAR EFFECTS OF ADENOSINE IN MAN : 199
ADENINE NUCLEOTIDE DEGRADATION IN THE HUMAN MYOCARDIUM DURING CARDIOPLEGIA : 200
RELEASE OF ADENOSINE FROM THE ISCHEMIC HUMAN HEART : 201
ACUTE ATTACK OF GOUT TRIGGERED BY ALLOPURINOL : 202
INTRACELLULAR PURINE AND PYRIMIDINE NUCLEOTIDE LYMPHOCYTES OF DIFFERENT MATURATION STAGES : 203
STEADY-STATE KINETICS OF THE REACTION CATALYZED BY GMP REDUCTASE : 204
ACYCLOVIR'S ANTIHERPETIC ACTIVITY IS POTENTIATED BY INHIBITION OF RIBONUCLEOTIDE REDUCTASE : 205
URATE OXIDASE ENCAPSULATED IN ERYTHROCYTES : 206
MURINE LYMPHOCYTES AND LYMPHOCYTE LINES SECRETE ADENOSINE DEAMINASE(ADA) : 207
AN EXPLANATION FOR THE HETEROGENEITY IN B LYMPHOCYTE ECTO-5′-NUCLEOTIDASE (ECT0–5′-NT) ACTIVITY IN PATIENTS WITH HYPOGAMMAGLOBULINEMIA : 208
ECTO-5′-NUCLEOTIDASE (ECTO-5′-NT) CAN USE IMP TO 209 PROVIDE THE TOTAL PURINE REQUIREMENTS OF MITOGEN-STIMULATED HUMAN T CELLS AND HUMAN B LYMPHOBLASTS : 209
A COMPARATIVE STUDY OF ALLOPURINOL AND PENTOSTAM IN THE TREATMENT OF VISCERAL LEISHMANIASIS : 210
REGULATION OF ENZYMES BY LIGAND INDUCED CHANGE IN POLYMERIZATION : 211
THE MECHANISM OF INSULIN-INDUCED INCREASE OF THE RATE OF DE NOVO PURINE BIOSYNTHESIS IN PRIMARY CULTURED RAT HEPATOCYTES : 212
THE EFFECTS OF URIDINE AND THYMIDINE ON THE DEGRADATION OF 5-FLUOROURACIL (5-FU), URACIL AND THYMINE BY RAT LIVER DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) : 213
THYMIDINE INCORPORATION IN NUCLEOSIDE TRANSPORT DEFICIENT T LYMPHOMA CELLS : 214
REGULATION OF PURINE BIOSYNTHESIS IN G1 PHASE ARRESTED MAMMALIAN CELLS : 215
MYOADENYLATE DEAMINASE DEFICIENCY : DIAGNOSIS BY FOREARM ISCHEMIC EXERCISE TESTING AND PLASMA PURINE MEASUREMENTS.
ADENYLOSUCCINASE DEFICIENCY : 217
218
219
220
DEAMINATION OF GUANINE TO XANTHINE : A METABOLIC PATHWAY OF UNDERESTIMATED IMPORTANCE IN HUMAN PURINE CATABOLISM?
KINETICS OF ALLOPURINOL TURNOVER AFTER I.V. INJECTION IN MAN AND ITS USE AS A MEANS TO ASSESS LIVER FUNCTION : 222
EFFECT OF FRUCTOSE ON THE CONCENTRATION OF PRPP IN ISOLATED RAT HEPATOCYTES : 223
DETECTION OF INHERITED ADENYLOSUCCINASE DEFICIENCY BY 2-DIM. THIN LAYER CHROMATOGRAPHY OF URINARY IMIDAZOLES : 224
CARRIER MEDIATED UPTAKE OF DEOXYGUANOSINE IN RAT LIVER MITOCHONDRIA : 225
226
227
FREQUENCY OF INTRAARTICULAR MONOSODIUM URATE (MSU) CRYSTALS IN ASYMPTOMATIC HYPERURICEMIC SUBJECTS : 228
ABERRANT ACTIVITY OF ADENOSINE DEAMINASE IN THE DIAMOND BLACKFAN SYNDROME : 229
ADENOSINE DEAMINASE DEFICIENCY AND CHONDRO-OSSEOUS DYSPLASIA : 230
ECTO-NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE ACTIVITY AND CALCIUM PYROPHOSPHATE DIHYDRATE CRYSTAL DEPOSITION DISEASE : 231
PHOSPHORYLATION OF PURINE DEOXYNOCLEOSIDES IN HUMAN T- AND B-LYMPHOBLASTS : 232
COMPARISON OF SURFACE DIFFERENTIATION ANTIGENS BETWEEN SEPARATED HGPRT-POSITIVE AND NEGATIVE T-CELL POPULATIONS FROM TWO LESCH-NYHAN HETEROZYGOTES : 233
2-COROADENOSINE IS PHOSPHORYLATED AND INCREASES THE PRODUCTION OF HYPOXANTHINE IN HUMAN CELLLS : 234
AN ALTERED HPRT PROTEIN, CREATED BY AN IN VITRO MUTAGENESIS OF THE GENE, CAN BE RECOGNIZED SPECIF : CALLY BY AN ANTIPEPTIDE ANTIBODY
INDUCTION OF COMPLETE REMISSION IN T-ALL BY DEOXYCO FARMYCIN (dcf) AND ARA-A : 236
IMPACT OF ASSOCIATED MEDICAL CONDITIONS ON CLINICAL FEATURES OF GOUT : 237
PURINE NUCLEOTIDE METABOLISM IN CULTURED RAT SKELETAL AND HEART MUSCLE : A COMPERATIVE STUDY OF THE MECHANISMS OF ATP CONSERVATION
Author Index to Abstracts