Reference Values for Sleep-Related Respiratory Variables in Asymptomatic European Children and Adolescents

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Abstract

Summary.

Aim: Only a limited number of studies, designed to establish normal values for sleep-related respiratory variables in children, have been reported, and all are non-European. The aim of this study was to expand the knowledge on normative data in children. Methods: Subjects ranging from 6 to 16 years were recruited and underwent full polysomnography. Only subjects without sleep disordered breathing or other sleep problems as assessed by clinical history were included. Results: Sixty subjects were studied ( = 11.7 ± 2.6 years; 28 boys; = 118.8 ± 30.6%). was 0.85 ± 1.06 (range: 0.0-5.5). was 0.06 ± 0.16 (range: 0.0-0.9); 11 patients had a total of 31 obstructive apneas. Only five obstructive hypopneas were detected with = 0.08 ± 0.17 (range: 0.0-0.9). was 1.98 ± 1.39 (range: 0.1-7.2). was 97.0 ± 0.6% (range: 96.0-98.0); was 91.8 ± 2.7% (range: 82.0-96.0); <% of total sleep time with SaO2 ± 95%> was 98.7 ± 2.1% (range: 90.8-100.0); was 0.8 ± 0.9 (range: 0.0-4.9) and was 6.1 ± 1.8 (range: 2.7-10.9). Snoring was detected in 15 patients (4 overweight subjects), with no difference in patient characteristics and sleep-related respiratory variables between snorers and non-snorers. Subjects in the overweight group (n = 22) had a lower SaO2nadir (90.8 ± 2.7 vs. 92.4 ± 2.6; P = 0.01) and a higher ODI (1.3 ± 1.3 vs. 0.4 ± 0.4; P = 0.0002) than their normal weight peers. Conclusion: Our data are in agreement with other non-European studies, designed to establish normal values in children.

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