Utility of Lumbar Puncture in Children Presenting With Status Epilepticus

    loading  Checking for direct PDF access through Ovid


ObjectivesBecause meningitis may trigger seizures, we sought to determine its frequency in children with first-time status epilepticus (SE).MethodsWe performed a retrospective cross-sectional study of children aged 1 month to 21 years who presented to a single pediatric emergency department between 1995 and 2012 with SE and who had a lumbar puncture (LP) performed as part of the diagnostic evaluation. We defined bacterial meningitis as a cerebrospinal fluid (CSF) culture positive for a bacterial pathogen or CSF pleocytosis (CSF white blood cells ≥10 cells/mm3) with a blood culture positive for a bacterial pathogen. We defined viral meningitis or encephalitis using a positive enterovirus or herpes simplex virus polymerase chain reaction test.ResultsAmong 126 children with SE who had an LP performed, 8 (6%) had CSF pleocytosis. Of these, 5 had received antibiotics before performance of a diagnostic LP. One child in the cohort was proven to have bacterial meningitis (0.8%; 95% confidence interval [CI], 0%–6%). Two other children had enteroviral meningitis (2/13 tested, 15%; 95% CI, 3%–51%), and 1 had a herpes simplex virus infection (1/47, 2%; 95% CI, 0%–15%).ConclusionsBacterial meningitis is an uncommon cause of SE.

    loading  Loading Related Articles