The study examined 2 plausible models of the predictive association between depressive symptoms and peer victimization, both physical and relational, with personality (Big Five), attachment style, and gender as moderators in a nonclinical sample of 282 Greek preadolescents. Results indicated that depressive symptoms, victimization, and Big Five traits were significantly associated. Moderation analyses indicated that only extraversion and perceived secure attachment moderated the relationship between victimization and depression. Preadolescents low on extraversion and those insecurely attached were more vulnerable to the negative effects of victimization on depression. High levels of conscientiousness moderated the negative influences of depression on victimization. Results are discussed in terms of their practical implications.