Cost effectiveness of statins: are the differences really important?

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With the clinical effectiveness of HMG CoA reductase inhibitors [statins] now well-established, pharmaceutical companies' thoughts increasingly turn to highlighting differences within the class - clinical, pharmacological and economical. Several studies presented at meetings over the last few months suggest that some newer statins are more cost effective than older members of the class. Nevertheless, a recent paper emphasises that, for primary prevention at least, the issues preventing wider statin prescribing may be more fundamental than relatively minor differences in cost effectiveness.

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