Prospective Comparison of Healing Rates and Therapy Costs for Conventional and Four-Layer High-Compression Bandaging Treatments of Venous Leg Ulcers

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To compare healing rates and associated treatment costs of four-layer high-compression bandaging (HCB) and conventional management (CM), as available on FP10, in the treatment of venous leg ulcers.


Randomized prospective study in which patients were allocated to one of two treatment groups.


Hospital-based leg ulcer service and community.


Thirty-six patients presenting with venous leg ulcers (30 compilers): 16 patients (nine female) in the HCB group and 14 patients (10 female) in the CM group.


A 12-week treatment period with either a four-layer HCB regime or CM.

Main outcome measures:

The significance of the difference between the number of ulcers healed, and associated treatment costs, was investigated using the Mann–Whitney U-test and survival analysis.


Four-layer HCB achieves a significantly (p = 0.003) higher healing rate of ulcers (75% of patients versus 21%) over a 12-week period. Weekly treatment costs for the four-layer therapy was significantly less than that of CM (mean difference in cost = £6.45, 95% CI = £1.22–11.68; p = 0.042).


It is more efficacious and economical for nurse specialists to treat patients presenting with leg ulcers with a four-layer HCB regime than for district nurses to carry out the standard palliative treatments available on GP prescription form FP10.

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