Cytotoxic Xenicane Diterpenes from the Brown AlgaPadina pavonia(L.) Gaill.

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Abstract

Column chromatography of the hexane fraction of a methanol extract ofPadina pavonia(L.) Gaill. collected from the Red Sea at Hurghada, Egypt yielded 18,19-epoxyxenic-19-methoxy-18-hydroxy-4-acetoxy-6,9,13-triene (1) and 18,19-epoxyxenic-18,19-dimethoxy-4-hydroxy-6,9,13-triene (2). The isolated compounds have various antitumor activities against lung carcinoma (H460) and liver carcinoma (HepG2) human cell lines(in vitro). Copyright © 2008 John Wiley & Sons, Ltd.

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