A Cross-sectional Study to Compare Hepatitis B Immunity in HIV-infected and HIV-uninfected Kenyan Children After Primary Hepatitis B Immunization

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Abstract

To evaluate protective antibody levels against hepatitis B surface antigen in HIV-infected and HIV-uninfected Kenyan children, this study enrolled 531 children. In the HIV-infected group, only 18.3% had protective hepatitis B surface antigen compared with 74.4% in the HIV-uninfected group (P < 0.0001). Perhaps HIV-infected children should be immunized differently.

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