Upwards and onwards
MITF pathway mutations in melanoma
GOLPH3 links the Golgi network to mTOR signaling and human cancer
Mysteries of salt and pepper
Seeing red : pheomelanin synthesis uncovered
Melanocytes out-foxed
Targeting mutant BRAF and KIT in metastatic melanoma : ASCO 2009 meeting report
Use of liposomes as drug delivery vehicles for treatment of melanoma
The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma
Evidence that stress to the epidermal barrier influenced the development of pigmentation in humans
Frequent mutations in the MITF pathway in melanoma
Id2 suppression of p15 counters TGF-β-mediated growth inhibition of melanoma cells
Met amplification and tumor progression in Cdkn2a -deficient melanocytes
Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport
Chemical analysis of late stages of pheomelanogenesis : conversion of dihydrobenzothiazine to a benzothiazole structure
Topical vitamin D3 analogues in the treatment of vitiligo
Lack of inherited mutations of PTPRD in familial melanoma and melanoma-astrocytoma syndrome
Program of the XVth PanAmerican Society for Pigment Cell Research
Cutaneous cholinergic system : lessons for skin pigmentary system
Vitamin D and melanin : driving forces for human evolution
Life and death in the balance : the role of NF-κB in interferon's biological actions
DNA damage responses : from molecular mechanisms to clinical interventions
Neuroendocrinology of the melanin pigmentary system
Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells
Melanosome biogenesis : construction of a dark organelle
PAX3 and SOX10 activate MET receptor expression in melanoma
Transgenic mice bearing high affinity TCR reactive to human melanoma epitope tyrosinase develop spontaneous depigmentation of the skin
Markedly enhanced expression of homing receptors by circulating Treg in melanoma
Modeling topical depigmentation in mice
Role of Marek's disease viruses in the expression of vitiligo in vitiligo-susceptible Smyth line chickens
Comparing the sensitivity of melanocytes and melanoma cells to bleaching phenols
p53 and pigmentation in mice : coordinating melanocyte and keratinocyte roles during the sunburn response
Autoinflammatory/autoimmune vitiligo in Smyth line chickens : Immune system- and melanocyterelated activities in feathers and in feather melanocytes isolated by laser capture microdissection
Mutation of Lyst in mice recapitulates aspects of human exfoliation syndrome
Effect of growth factors and keratinocyte conditioned media on the migration of normal human epidermal melanocytes
Oncogenic BRAF regulates neuronal differentiation of melanoma by epigenetic and transcription repressor HES1-dependent mechanisms
Retonic acid induces the inhibitor SFRP1 in human melanoma
Transcription factor activator protein 2 Epsilon (TFAP2E) functions redundantly with TFAP2A to promote differentiation of melanocytes in zebrafish embryos
Importance of EZH2 for the suppression of cellular senescence in melanocytes and melanoma cells
α -MSH Increases H2AX phosphorylation soon after UV irradiation in human melanocytes
Correlation of the MC1R genotype with the UV response of human melanocytes : Implications on melanoma susceptibility
Two ion channels associated with a Parkinsonism, TRPM2 and TRPM7, contribute to tolerance of oxidative stress in melanocytes
Melanin detection in human skin biopsies using multispectral imaging
Autophagy in cutaneous malignant melanoma
Alpha-MSH Is an important participant in the early responses of human melanocytes to UV-induced oxidative stress
Functional properties and characterization of melanocyte label-retaining cells
F-box protein co-factors Cks1 and α B-crystallin : B-RAF regulation and roles in melanoma cell cycle progression
Differential signaling requirement for the maintenance of non-cutaneous and dermal melanocytes versus epidermal melanocytes
Enhanced melanocyte proliferative response accompanies tumour initiation by UVR in neonatal melanoma-prone mice
Interaction between the transcription factor, Sox10, and Endothelin receptor B in the melanocyte lineage
A role of MiTF in UVR-mediated DNA damage response via p21CIP1 in normal human melanocytes and melanoma cells
Eumelanin molecular recognition : toward a fundamental understanding and environmental applications
Cross-talk between GPCRs signaling pathways in melanocytes reveal PKC-beta as a potential target for the rescue of Mc1r deficient pigmentation phenotypes
Study of melanocytes mechanical properties by nano-indentation uncover membrane plasticity behavior
Characterization of the unfolded protein response in melanocytes and melanoma
Nuclear magnetic resonance analysis of metabolic changes in human and hamster melanoma cells before after induction of melanogenesis
The expression of dickkopf1 (DKK1) in palmoplantar skin is upregulated in vivo
The biological activity of vitamin D3 hydroxyderivatives and expression of vitamin D receptor are attenuated after induction of melanin synthesis in melanoma cells
3 β -Hydroxy-androsta-5,7-diene-17 β -carboxylic acid, a novel steroidal 5,7-diene derivative, inhibits proliferation in melanoma cell lines and HaCaT keratinocytes
The normoxic expression of HIF-1 α in human melanoma cells : Biologic effects and lack of regulation of the Erk 1/2 MAPK pathway
New secosteroidal (vitamin D-like) derivatives as potential anti-melanoma therapeutics
20-hydroxyvitamin D2, a product of cytochrome P450scc hydroxylation, inhibits proliferation of human melanoma cells and keratinocytes
Role of nNOS in melanoma progression
MDA MB 435 melanoma cell line - derived cancer stem cells (CSC) show increase in expression of ABC transporter family drug resistance genes not previously implicated in tumor growth and progression
Characterization of the UDP-glucuronosyltransferases (UGTs) in melanocytes and melanoma
New class of tubulin binding compounds showed good activity against melanoma both in vitro and in vivo
Epigenetic silencing and reactivation of RAR β 2 in human melanoma cells
The correlation of TRPM1 (Melastatin) mRNA expression with microphthalmia associated transcription factor (MITF) and other melanogenesis related proteins in normal and pathological skin, hair follicles, and melanocytic nevi
Selenium for the prevention and treatment of melanoma
Transition from primary to metastatic melanoma is associated with differential expression of genes regulating intracellular levels of glutathione (GSH)
Retinoid-X-Receptor α (RXR α ) signaling in tumormicroenvironment during melanoma formation
The Melanocortin 1 receptor (Mc1R) mediates cellular responses to UVR by enhancing the clearance of UV-induced DNA lesions
Mc1r has a role in the repair of UV induced oxidative damage in melanocytes
Development of mammalian assays to screen for potential pigmentation modulating agents
Growth of melanocortin-1 receptor defective primary murine melanocytes with conditioned media containing stem cell factor
Ref-1 deficiencies in nuclear regulatory function are associated with less malignant human melanoma phenotypes
Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma
Unraveling the molecular mechanisms of senile lentigines
Selective regulation of mitochondrial Bcl-2 family in melanoma by Cytotech Labs API 31510
Eruptive nevi due to α-MSH stimulation
Transcriptome analyses uncover novel cellular defects in vitiligo lesional skin
The expression of acute phase reactant proteins correlates with melanoma invasion and predicts poor survival in Stage III and Stage IV melanoma
Melanin production and dispersion in human skin following repetitive exposure to UVA, UVB or SSR
Melanoma : Is hair the root of the problem?
Why do melanomas get so dark?
Replacement of a large minority of smooth muscle cells by melanocytes during development in the ductus arteriosus does not allow its closure and leads to postnatal death
Xeroderma pigmentosum (XP)-C and XPC knockdown keratinocytes as a model to study the effects of ROS in photoprotection and cancer
Long term survival in patients with large ciliary body and choroidal melanomas treated with iodine-125 plaque brachytherapy
Quantitative analysis of gene regulation in response to serial oxidative stress in the retinal pigment epithelium : molecular proportional-integral-derivative control of gene expression?