Is dopamine still the key to treating schizophrenia?

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Current antipsychotics are useful in treating schizophrenia but do not offer a complete solution to managing the illness. Recent research suggests that modifying targets upstream of dopamine receptor blockade may hold the key to an improved psychopharmacological approach, explained Dr Oliver Howes, Honorary Consultant Psychiatrist at the South London and Maudsley NHS Foundation Trust, speaking at a satellite symposium organised by Roche at the 12th Latest Advances in Psychiatry meeting in London in March. Steve Titmarsh reports.

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