Evaluation of the New OneTouch Verio Versus FreeStyle Lite Glucose Meter and the Beckman DxC800 Laboratory Analyzer

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Johnson & Johnson released the OneTouch Verio strip in September 2010. Here we compare the performance of this new meter with the modified Abbott FreeStyle Lite meter using capillary, venous lithium heparin whole blood, venous lithium heparin plasma, and serum in accordance with International Standards Organization 15197 criteria.


The evaluation included imprecision, patient comparison, and interference studies. Both healthy and diabetic participants were recruited, and the results of the 2 meters were compared with the Beckman DxC800 glucose method. The interferences tested included galactose, maltose, lactose, Icodextrin, Intragam, paracetamol, ascorbic acid, hematocrit, hemolysis, lipemia, and variable storage temperature.


The imprecision at all levels for the 2 meters was less than 5%. With the finger prick capillary samples, there was 80% and 83% compliance with the International Standards Organization guideline not the 95% or greater recommended, with a mean difference of 0.6 and −0.4 mM by the OneTouch Verio and FreeStyle Lite meters, respectively. Ascorbic acid was the only interference common to both meters. The OneTouch Verio suppresses and reports an error with affected results, but the FreeStyle Lite reports a falsely elevated result without warnings. Hematocrit at very high levels produced low results with the FreeStyle Lite strip only.


The OneTouch Verio analytically performed well. Owing to the differences between the 2 meters, it is best that the 2 meters not be used interchangeably. One type of meter should be consistently used to ensure accurate monitoring. The interference studies showed that, apart from slight differences with ascorbic acid and hematocrit, the 2 meters were unaffected by any of the compounds tested.

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