The disaster response following the 2010 earthquake in Port-au-Prince, Haiti, was the largest in history. Point-of-care testing played a significant role in patient care in the immediate response. The medical needs of the Haitian population remain significant after the emergency response has abated. This article describes how point-of-care devices similar to those used in the disaster response can be used to establish a laboratory able to support a medical center in a resource-poor environment. Such a laboratory can allow for lifesaving medical treatments such as mechanical ventilation until the laboratory is able to maintain more traditional bench-top analyzers.