Progressive and disabling lipoatrophy associated with insulin aspart via a continuous subcutaneous insulin infusion

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Since the advent of insulin analogues, the incidence of insulin-induced lipoatrophy has been relatively rare save for a small number of isolated cases. We report a case of severe disfiguring lipoatrophy in an 18-year-old female patient following a change in the mode of administration of insulin aspart from subcutaneous injections to continuous subcutaneous insulin infusion (CSII).This case highlights the need for further research into the causes of insulin-induced lipoatrophy and the need for caution when starting a patient on a CSII. Copyright © 2015 John Wiley & Sons.

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