Psychologists are regularly confronted by a wide range of ethical challenges for which no clear solution is apparent. Although the “Ethical Principles of Psychologists and Code of Conduct” (American Psychological Association, 2002) is of some help when one faces such dilemmas, it cannot provide definitive guidance or all needed answers. The process of ethical decision making is reviewed, and the use of different models for ethical decision making is explored. Case examples highlight representative challenges faced by psychologist practitioners. Three invited experts provide commentaries in response to the points made and questions raised. They discuss ethical decision making from their perspectives and make recommendations to practitioners for how they can conceptualize and address the dilemmas they will face in their practices.