IN THIS ISSUE
Engineering antibody fragments to fold in the absence of disulfide bonds
Investigating protein unfolding kinetics by pulse proteolysis
Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility
Walker-A threonine couples nucleotide occupancy with the chaperone activity of the AAA+ ATPase ClpB‡
Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis : Crystal structures of the substrate-free and quaternary complex enzymes
Crystal structure of domain-swapped STE20 OSR1 kinase domain
Nonenzymatic biotinylation of histone H2A
Design of a heterotetrameric coiled coil
Residual structure within the disordered C-terminal segment of p21Waf1/Cip1/Sdi1 and its implications for molecular recognition
An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen
StoneHinge : Hinge prediction by network analysis of individual protein structures
Genetic selection system for improving recombinant membrane protein expression in E. coli
Selection and structural analysis of de novo proteins from an α3β3 genetic library
Random dissection to select for protein split sites and its application in protein fragment complementation
Dynamics of a truncated prion protein, PrP(113–231), from 15N NMR relaxation: Order parameters calculated and slow conformational fluctuations localized to a distinct region
Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn
Parallel screening and optimization of protein constructs for structural studies
Re-engineering a β-lactamase using prototype peptides from a library of local structural motifs†
The strong dimerization of the transmembrane domain of the fibroblast growth factor receptor (FGFR) is modulated by C-terminal juxtamembrane residues
Unique interactions between the chromophore and glutamate 16 lead to far-red emission in a red fluorescent protein
Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion
A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding