Synthesis of Novel Mammalian Metabolites of the Isoflavonoid Phytoestrogens Daidzein and Genistein

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Abstract

Abstract.

The synthesis of novel mammalian metabolites of dietary isoflavones, dihydrodaidzein (4′,7-dihydroxyisoflavanone) 7,2 dihydrogenistein (4′,5,7-trihydroxyisoflavanone) 9, 6′-hydroxy-O-demethylangolensin [1-(2,4,6-trihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one] 10, and cis- and trans-4′,7-dihydroxyisoflavan-4-ols 11, 12 is described, and their characteristics by physical and chemical constants given for the first time.

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