Alternate ways of administering antidepressants when oral intake is impossible are discussed.Method
Reviews of 1) the medical circumstances that preclude oral medication administration and 2) novel administration strategies for antidepressants were conducted.Results
Consultation psychiatrists not infrequently encounter depressed patients who lack a functioning gastrointestinal tract and who thus cannot absorb oral antidepressant medication. Under these circumstances, antidepressants can be administered intravenously, by rectal suppository, or topically.Conclusion
There are options for administration of antidepressant medication when oral intake is impossible.