Antidepressants for the Virtually Eviscerated Patient: Options Instead of Oral Dosing

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Abstract

Objective

Alternate ways of administering antidepressants when oral intake is impossible are discussed.

Method

Reviews of 1) the medical circumstances that preclude oral medication administration and 2) novel administration strategies for antidepressants were conducted.

Results

Consultation psychiatrists not infrequently encounter depressed patients who lack a functioning gastrointestinal tract and who thus cannot absorb oral antidepressant medication. Under these circumstances, antidepressants can be administered intravenously, by rectal suppository, or topically.

Conclusion

There are options for administration of antidepressant medication when oral intake is impossible.

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