Antidepressants for the Virtually Eviscerated Patient: Options Instead of Oral Dosing

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Alternate ways of administering antidepressants when oral intake is impossible are discussed.


Reviews of 1) the medical circumstances that preclude oral medication administration and 2) novel administration strategies for antidepressants were conducted.


Consultation psychiatrists not infrequently encounter depressed patients who lack a functioning gastrointestinal tract and who thus cannot absorb oral antidepressant medication. Under these circumstances, antidepressants can be administered intravenously, by rectal suppository, or topically.


There are options for administration of antidepressant medication when oral intake is impossible.

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