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Seventeen males with spinal cord injury (SCI) and their partners, screened for suitability for pharmacological intervention for erectile dysfunction, were assessed pre- and post-intervention on measures of marital, social, personality, and sexual functioning. Intervention did not impact general measures of life satisfaction or personality functioning. A positive impact on a general measure of marital satisfaction and on several measures of sexual functioning was noted, generally more so for SCI males than their partners. Implications for future studies and sexual counseling are discussed.