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Life satisfaction is a major component of quality of life. Satisfaction scores of 38 individuals at 6 months post-stroke were compared to disability ratings measured by the Functional Independence Measure and handicap ratings measured by the Craig Handicap Assessment and Reporting Technique. Satisfaction was lower than for the general population, and more strongly associated with disability than handicap. Satisfaction scores of the patients' primary caregivers were compared to a measure of caregiver stress and to caregivers' ratings of the patients' disability and handicap. Caregivers' satisfaction was (1) somewhat lower than satisfaction in the general population; and (2) directly associated with caregiving stress scores, which were in turn associated with patients' level of handicap, particularly amount of physical assistance required, mobility in home and community, and ways of spending time. Research is needed to track these relationships longitudinally.