|| Checking for direct PDF access through Ovid
To evaluate the relationship between caregiver-specific social support and adherence to disease-modifying therapies (DMT) for multiple sclerosis (MS).Telephone survey with 6 monthly follow-up assessments.Veterans Health Administration.54 veterans with MS who identified a primary caregiver and who were currently prescribed DMT.Demographic information. Caregiver supportive and conflictual qualities were assessed with the Quality of Relationships Inventory—Short Form. Medication-specific support was assessed with 4 items developed from qualitative focus groups. DMT adherence was assessed with a single item that requested missed doses in the past month.Adherence in this population of ongoing DMT users was relatively high, with 85.1% (95% confidence interval = 75.6%–94.8%) reporting adherence ≥80% of prescribed doses. Using logistic regression adjusting for disability, type of DMT, and length of time on current DMT, the authors predicted longitudinal adherence by supportive qualities of the caregiver–care recipient relationship but not by conflictual qualities or medication-specific support.Supportive qualities of the caregiver–care recipient relationship represent an important predictor of DMT adherence and a potential target in adherence-based interventions.