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The accuracy of 11 scales from the Minnesota Multiphasic Personality Inventory (MMPI) for the identification of individuals prone to substance abuse has been established from previous research. This study evaluated the sensitivity of these scales to current substances abuse. Participants were 137 males receiving inpatient services for substance abuse at a Veterans Administration Medical Center. Patients took the MMPI within 48 hr of admission and again after 4 weeks. As predicted, inpatient treatment and abstinence did not result in reliable decreases in scores on any substance abuse scales. Therefore, these scales did not appear to be appropriate measures of change as a result of intervention.